Dr. Myra Wilkerson, an expert in laboratory medicine, discusses the importance of choosing the right benchmarking approach for your institution. She advises against accepting institutionally imposed benchmarks, often favored by CFOs, which may not account for the nuances of laboratory medicine. Instead, she suggests finding a company that specializes in benchmarking diagnostic laboratory performance or can provide clinical laboratory productivity benchmarks. It is important the company can provide tailored benchmarks for your laboratory based on factors such as the type of laboratory and supply chain benchmarks. Other factors to consider include the essential test menu for your site, market opportunities, and unique ranges for productivity for each individual site. By fighting back against one-size-fits-all laboratory benchmarking, institutions can better meet the needs of their patients and local clinicians.